November 2017Research at the Lady Davis Institute

Awards from the Canadian Institutes of Health Research

In the most recent round of funding by the Canadian Institutes of Health Research (CIHR), the following researchers in the Lady Davis Institute at the JGH were awarded project grants:

Dr. Stéphane Richard received a CIHR Foundation Grant worth $3.5 million over seven years for “Molecular and Genetic Analysis of Arginine Methylation and RNA Binding proteins in Health and Disease.”

Dr. Jonathan Afilalo: $1.1 million for a four-year clinical study, “Protein and Exercise to Reverse Frailty in Older Men and women undergoing Transcatheter Aortic Valve Replacement: The PERFORM-TAVR Trial.”

Dr. Mark Basik: $952,000 over five years for “Innovative pre-clinical models to overcome drug resistance in triple negative breast cancer.”

Dr. Andréa LeBlanc: $925,000 over five years for “Validation of the Nlrp1-Casp1-Casp6 pathway as an early therapeutic target of age-dependent cognitive impairment and Alzheimer Disease.”

Dr. Alexandre Orthwein: $850,000 over five years for “Regulation of DNA double-strand break repair pathways in multiple myeloma.”

Dr. Volker Blank: $800,000 over five years for “Regulation and function of NFE2L3: linking transcription factor activity to tumorigenesis.”

Dr. Kristian Filion: $175,000 over two years for “Tramadol and the Risk of Adverse Cardiovascular Events: A Population-based Study.”

Dr. Antonis Koromilas: $100,000 for one year for “Mechanisms and therapeutic implications of PKR and eIF2 phosphorylation in HER2 breast tumour suppression.”

Dr. Michael Pollak: $100,000 for one year for “Direct targeting of translation machinery in cancer treatment.”

Dr. Brett Thombs: $75,000 for one year for “Improving Depression Screening in Geriatric Patients by Reducing Bias and Generating Individualized Accuracy Estimates: An Individual Patient Data Meta-Analysis of the Geriatric Depression Scale (GDS).”

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